Cu(II)-aza(bisoxazoline)-catalyzed asymmetric benzoylations |
| |
| Authors: | Gissibl Anja Finn M G Reiser Oliver |
| |
| Affiliation: | Institut für Organische Chemie der Universit?t Regensburg, Universit?tsstrasse 31, D-93053 Regensburg, Germany. |
| |
| Abstract: | [reaction: see text] Racemic 1,2-diols and alpha-hydroxy carbonyl compounds can be asymmetrically benzoylated in a kinetic resolution in the presence of various Cu(II)-aza(bisoxazoline) catalysts. A novel bisbenzyl-substituted aza(bisoxazoline) ligand proved to be especially effective when immobilized on MeOPEG(5000), giving from 91 to > or = 99% ee in 37-49% yield for each of five sequential reactions. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
