Nucleophilic partners in the tandem conjugate addition-Dieckmann condensation reaction: 1. synthesis of 1,2,3-trisubstituted naphthalenes |
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| Authors: | Martinez Aaron D Deville Jay P Stevens Joel L Behar Victor |
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| Affiliation: | Department of Chemistry MS-60 Rice University, Houston, Texas 77251-1892, USA. |
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| Abstract: | The scope and limitations of the tandem conjugate addition-Dieckmann condensation for the construction of 1,2,3-trisubstituted naphthalenes is defined. Viable nucleophilic partners in this methodology include organocuprates, active methylenes, and a variety of heteroatom initiators. |
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