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Synthesis of the enantiomer of the antidepressant tranylcypromine |
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| Authors: | René Csuk Magda J Schabel Yvonne von Scholz |
| Institution: | a Institut f. Organ. Chemie, Martin-Luther Universität Halle-Wittenberg, Kurt-Mothes Strasse 2, D-06120, Halle (Saale, Germany b Pharm.-Chemisches Institut, Ruprecht-Karls Univesität Heidelberg, Im Neuenheimer Feld 364, D-69120, Heidelberg, Germany |
| Abstract: | Both enantiomers of the antidepressant tranylcypromine, trans 2-phenyl-cyclopropy-lamine 1, were prepared in enantiomerically pure form by a chemoenzymatic approach starting from racemic (±)-(1RS, 2RS)-trans ethyl 2-phenyl-cyclopropane carboxylate (±)-3. |
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