Gas chromatographic analysis of bifunctional amines after derivatization with methyldichlorophosphine and sulfur |
| |
| Authors: | K Jacob G Schnabl W Vogt |
| |
| Institution: | 1. Institut für Klinische Chemie am Klinikum Grosshadern der Universit?t München, Postfach 70 12 60, 8000, München 70, FRG
|
| |
| Abstract: | Summary A derivatization procedure for the gas chromatographic analysis of bifunctional amines likeβ-adrenergic blocking drugs is described. The method consists of a two-step reaction with methyldichlorophosphine and sulfur
in presence of triethylamine to form cyclic methylphosphonothioic derivatives. The properties of these compounds are discussed
and the application of the method to the quantitation of ephedrine in human body fluids is presented.
Presented at the 15th International Symposium on Chromatography, Nürnberg, October 1984 |
| |
| Keywords: | Gas chromatography Derivatization Bifunctional amines Ephedrine Methyldichlorophosphine |
| 本文献已被 SpringerLink 等数据库收录！ |
