Abstract: | Substituted thioureas have attracted much attention due to their herbicidal1, antibacterial2, anti-HIV3 and plant-growth regulating4 activity. Meanwhile substituted ureas are not only used as medicines and agrochemicals because of their antiinflammatory5, analgesic5 and insectcidal6 activity, but also used as intermediates for the synthesis of many important heterocyclic compounds. In addition, 5-aryl-2-furoic acid derivatives have been used as antibacterial agent7, local anesthesia8, analgesic9 and plant-growth regulator10. Therefore, with the objective of obtaining new biologically active compounds, it is necessary to investigate the convenient and efficient method to prepare new compounds bearing 5-aryl-2-furoyl and thiourea or 5-aryl-2-furoyl and urea moieties. |