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Synthesis of alkyl glycerolipids with various cationic groups linked directly to the glycerol backbone
Authors:M. A. Maslov  E. V. Sycheva  N. G. Morozova  G. A. Serebrennikova
Affiliation:(1) M. V. Lomonosov Moscow State Academy of Fine Chemical Technology, 86 prosp. Vernadskogo, 117571 Moscow, Russian Federation
Abstract:A number of positively charged lipids containing pyridinium,N-methylmorpholinium,N-methylimidazolinium, 4-N,N-dimethylaminopyridinium, and 4-N,N-dimethylcyclo-hexylammonium groups linked directly to the C(3) atom of 1,2-di-O-alkylglycerols with Br, MsO, and TsO anions as counterions were synthesized. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1381–1384, July, 1999.
Keywords:cationic lipids  alkyl glycerolipids  transfection
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