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An improved synthesis of releasable luciferin-CPP conjugates
Authors:Emelí  a Eirí  ksdó  ttir
Affiliation:Department of Neurochemistry, The Arrhenius Laboratories for Natural Sciences, Stockholm University, SE-106 91 Stockholm, Sweden
Abstract:We have improved the synthesis of a previously published luciferin-linker, used in an assay enabling rapid real-time quantification of luciferin-CPP conjugate uptake and cytosolic cargo release. We also present the synthesis of a new luciferin-linker with the same conjugation ability. Both luciferin-linkers are now available via an efficient one-pot procedure.
Keywords:Luciferin   Luciferin-linker   Conjugate   Cell-penetrating peptide   Releasable luciferin
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