An improved synthesis of releasable luciferin-CPP conjugates |
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Authors: | Emelí a Eirí ksdó ttir |
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Affiliation: | Department of Neurochemistry, The Arrhenius Laboratories for Natural Sciences, Stockholm University, SE-106 91 Stockholm, Sweden |
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Abstract: | We have improved the synthesis of a previously published luciferin-linker, used in an assay enabling rapid real-time quantification of luciferin-CPP conjugate uptake and cytosolic cargo release. We also present the synthesis of a new luciferin-linker with the same conjugation ability. Both luciferin-linkers are now available via an efficient one-pot procedure. |
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Keywords: | Luciferin Luciferin-linker Conjugate Cell-penetrating peptide Releasable luciferin |
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