Simple and facile method for the preparation of vinyl azides |
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Authors: | Vikas N. Telvekar Balaram S. Takale Harshal M. Bachhav |
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Affiliation: | Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai 400 019, India |
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Abstract: | A synthetic utility of [bis(trifluoroacetoxy)iodo]benzene on α,β-unsaturated carboxylic acid is described. This is the first example of preparation of vinyl azide using α,β-unsaturated carboxylic acids directly by using hypervalent iodine reagent. The advantage of this protocol is characterized with non-toxicity of starting material and shorter reaction times to obtain good preparative yields. The method is also useful for the preparation of acyl azides. |
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Keywords: | [Bis(trifluoroacetoxy)iodo]benzene Sodium azide Carboxylic acids Vinyl azides |
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