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Total synthesis of the natural isoprenylcysteine carboxyl methyltransferase inhibitor spermatinamine |
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| Authors: | José García |
| Institution: | Departamento de Química Orgánica, Facultade de Química. Universidade de Vigo, 36310 Vigo, Spain |
| Abstract: | The first total synthesis of spermatinamine, an inhibitor of isoprenylcysteine carboxyl methyltransferase (Icmt) with a bromotyrosine-spermine-bromotyrosine dimeric structure is described. |
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