Kröhnke reaction in aqueous media: one-pot clean synthesis of 4′-aryl-2,2′:6′,2″-terpyridines |
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| Authors: | Shujiang Tu Runhong Jia Junyong Zhang Changsheng Yao |
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| Affiliation: | a Department of Chemistry, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China
b College of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215006, PR China |
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| Abstract: | A clean aqueous Kröhnke reaction process has been accomplished via a one-pot procedure of 2-acetylpyridine with aromatic aldehyde and ammonium acetate under microwave irradiation or conventional heating conditions. This method is convenient, economic and environmental friendly. |
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