A new asymmetric synthetic route to substituted piperidines |
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| Authors: | M. Somi Reddy |
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| Affiliation: | Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500007, Andhra Pradesh, India |
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| Abstract: | An asymmetric synthesis of substituted piperidines has been described. β-Cyclodextrin- or oxazaborolidine-catalyzed asymmetric reduction of α-azido aryl ketones to the corresponding alcohols has been employed as the key step along with ring closing metathesis and selective dihydroxylation. |
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| Keywords: | 1-Aza sugars β-Cyclodextrin Oxazaborolidine Ring closing metathesis Dihydroxylation |
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