Biotransformation of ferulic acid into two new dihydrotrimers by Momordica charantia peroxidase

As a result of a continuing investigation of the biotransformation of ferulic acid with H2O2/Momordica charantia peroxidase at pH 5.0 in the presence of acetone, triFA1 (1) and triFA2 (2), two new FA dehydrotrimers, have been isolated. The structures were elucidated from the spectroscopic data including 2D-NMR such as HSQC, HMBC and NOESY data. TriFA1 (1) is a unique FA dehydrotrimer possessing a 3a,9b-dihydro-1H-furo3,4-c]1]benzopyran-3(4H)-one ring system. The possible mechanism for the formation of triFA1 was also discussed.