One pot synthesis of the dinucleoside phosphonate GpCH2U |
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| Authors: | A Haikal J Doumen L Wyns |
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| Institution: | (1) Institute voor Moleculaire Biologie, Vrije Universiteit Brussel, Brussels, Belgium;(2) Present address: Faculity of Science, Department of Chemistry, Zagazig University, Zagazig, Egypt |
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| Abstract: | Summary The preparation of the dinucleoside phosphonate GpCH2U, starting from the isosteric phosphonate analogue of uridine (3) and the guanosine derivative5 is described.
Eintopfsynthese des Dinucleosidphosphonats GpCH2U Zusammenfassung Die Herstellung des Dinucleosidphosphonats GpCH2U aus dem isosteren Phosphonatanalogen von Uridin (3) und dem Guanosinderivat5 wird beschrieben. |
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| Keywords: | Dinucleoside phosphonate Ribonuclease T1 Cocrystallization |
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