Nickel-catalyzed arylation of acrolein diethyl acetal: a substitute to the 1,4-addition of arylhalides to acrolein |
| |
| Authors: | Condon S Dupré D Nédélec J Y |
| |
| Affiliation: | Laboratoire d'Electrochimie, Catalyse et Synthèse Organique, CNRS-Université Paris XII-UMR 7582, 2 rue Henri Dunant, 94320 Thiais, France. condon@glvt-cnrs.fr |
| |
| Abstract: | [reaction: see text] In the presence of catalytic amount of NiBr(2) as catalyst precursor, organic halides are reductively coupled at 70 degrees C with acrolein diethyl acetal to give (Z)- and (E)-enolethers by allylic deplacement of an alkoxy group. Subsequent hydrolysis affords beta-arylated aldehydes. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
