Asymmetric conjugate addition reactions of Meldrum's acid derived acceptors employing chiral phosphoramidite ligands |
| |
| Authors: | Watanabe Takumi Knöpfel Thomas F Carreira Erick M |
| |
| Affiliation: | Laboratorium für Organische Chemie, ETH-H?nggerberg HCI H335, CH-8093 Zürich, Switzerland. |
| |
| Abstract: | [reaction: see text] The enantioselective conjugate addition reaction of Et(2)Zn to Meldrum's acid derived acceptors, mediated by a catalyst formed from Cu(O(2)CCF(3))(2) and a phosphoramidite ligand, is reported. Adducts are obtained in useful yields and up to 94% ee. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
