Convenient access to polysubstituted 1-indanones by Sc(OTf)3-catalyzed intramolecular Friedel-Crafts acylation of benzyl Meldrum's acid derivatives |
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| Authors: | Fillion Eric Fishlock Dan |
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| Institution: | Department of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada. efillion@uwaterloo.ca |
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| Abstract: | reaction: see text] The intramolecular Friedel-Crafts acylation of benzyl Meldrum's acids is catalyzed by Sc(OTf)(3) under mild reaction conditions. Several polysubstituted 1-indanones have been prepared. |
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