| 1-烷基-2-甲基咪唑衍生物的高效简便合成 |
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| 引用本文： | 宋光富,彭黔荣,杨敏,谢如刚.1-烷基-2-甲基咪唑衍生物的高效简便合成[J].化学研究与应用,2006,18(5):542-544. |
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| 作者姓名： | 宋光富 彭黔荣 杨敏 谢如刚 |
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| 作者单位： | 贵州大学化学工程学院,贵州,贵阳,550003;贵州黄果树烟草集团公司技术中心,贵州,贵阳,550003;四川大学化学学院,四川,成都,610064 |
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| 摘 要： | 本文优化了溴乙烷与2-甲基咪唑的N-烷基化反应条件,并且高收率地合成了一系列具有抗菌活性的1-烷基-2-甲基咪唑衍生物。
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| 关 键 词： | 咪唑 N-烷基化 1-乙基-2-甲基咪唑 抗菌活性 |
| 文章编号： | 1004-1656（2006）05-0542-03 |
| 收稿时间： | 2005-12-06 |
| 修稿时间： | 2006-01-26 |
Convenient and efficient synthesis of 1-alkylated-2-methylimadazole derivatives |
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| SONG Guang-fu,PENG Qian-rong,YANG Min,XIE Ru-gang.Convenient and efficient synthesis of 1-alkylated-2-methylimadazole derivatives[J].Chemical Research and Application,2006,18(5):542-544. |
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| Authors: | SONG Guang-fu PENG Qian-rong YANG Min XIE Ru-gang |
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| Institution: | 1. Department of Chemical Engineeming, Guizhou University, Guiyan 550003, China ; 2. Technology Center Guizhou Huangguoshu Group,Guiyang 550003, China; 3. Department of Chemistry, Sichuan University, Chengdu 610064, China |
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| Abstract: | The reactive conditions of N-alkylation for bromoethane and 2-methylimi-dazole were optimized,and a series of derivatives of 1alkylated-2-methylimidazole which have antibacterial activity were synthesized in this paper. |
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| Keywords: | N-alkylation of imidazole 1-ethyl-2-methylimidazole antibacterial activity |
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