A one-step synthesis of 2-Alkyl-5-hydroxychromones and 3-Alkoyl-2-alkyl-5-hydroxychromones |
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| Authors: | Okombi Sabrina Schmidt Julien Mariotte Anne-Marie Perrier Eric Boumendjel Ahcène |
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| Institution: | Département de Pharmacochimie Moléculaire UMR-CNRS 5063, Université Joseph Fourier de Grenoble, Faculté de Pharmacie, Meylan, France. |
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| Abstract: | 2-Alkyl-5-hydroxychromones (2-alkyl-5-hydroxy-4-oxo-4H-1-benzopyran) and 3-alkoyl-2-alkyl-5-hydroxychromones (3-alkoyl-2-alkyl-5-hydroxy-4-oxo-4H-1-benzopyran) were prepared in one-step and one pot reaction by condensation of 2',6'-dihydroxyacetophenone with an alkoyl chloride in the presence of K2CO3. |
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