Three New Bisabolocurcumin Ethers from the Rhizomes of Curcuma longa L. |
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Authors: | Yun‐Chuan Xiao Jun Lei Miao Liu Min Yu Jian Ran Jing Xie Wei Li Jing Huang |
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Institution: | 1. West China School of Pharmacy, Sichuan University, 17th, 3 duan, Renminnanlu Road, Chengdu 610041, P.?R. China (phone/fax: +86‐28‐85503045);2. School of Chemistry and Chemical Engineering, Mianyang Normal University, Mianyang 621000, P.?R. China;3. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, P.?R. China |
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Abstract: | Three new bisabolocurcumin ethers, named demethoxybisabolocurcumin ether ( 1 ), bisabolocurcumin ether ( 2 ), and didemethoxybisabolocurcumin ether ( 3 ), along with two known compounds, 4 and 5 , were isolated from the AcOEt extract of the rhizomes of Curcuma longa L. Their structures were established by the analysis of NMR and MS data. The new compounds 1 – 3 , which possess a new 1,7‐diarylheptanoid skeleton linked with a bisabolone‐type sesquiterpene substructure by a C? O bond, were found for the first time in a natural source. |
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Keywords: | Curcuma longa Bisabolones Bisabolocurcumin ether Demethoxybisabolocurcumin ether Didemethoxybisabolocurcumin ether |
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