Uncatalyzed and solvent-free one-pot three component synthesis of α-amino phosphonates |
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Authors: | M Hosseini-Sarvari |
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Institution: | 1.Department of Chemistry, College of Science,Shiraz University,Shiraz,Iran |
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Abstract: | An innovative route to preaper a number of variously substituted α-aminophosphonate is presented. The protocol avoids the use of any catalyst, organic solvents, and dry reaction conditions. The synthesis of α-aminophosphonates in the present study represents a three-component reaction in which no intermediate formation of either an imine or α-hydroxy phosphonate was observed. |
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