Norlignans and Phenylpropanoids from Metasequoia glyptostroboides Hu et Cheng |
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| Authors: | Qi Zeng Xiang‐Rong Cheng Jiang‐Jiang Qin Bin Guan Rui‐Jie Chang Shi‐Kai Yan Hui‐Zi Jin Wei‐Dong Zhang |
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| Affiliation: | 1. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, P.?R. China, (phone/fax: +86‐21‐34205989);2. King Saud University, Riyadh 11451, Saudi Arabia;3. Department of Phytochemistry, Second Military Medical University, Shanghai 200433, P.?R. China |
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| Abstract: | Five new compounds, i.e., the three new norlignans metasequirins G–I ( 1 – 3 ) and the two new phenylpropanoids 7‐(3‐ethoxy‐5‐methoxyphenyl)propane‐7,8,9‐triol (=1‐(3‐ethoxy‐5‐methoxyphenyl)propane‐1,2,3‐triol; 4 ) and 7‐(3‐hydroxy‐5‐methoxyphenyl)propane‐7,8,9‐triol (=1‐(3‐hydroxy‐5‐methoxy‐phenyl)propane‐1,2,3‐triol; 5 ), were isolated from the branches and stems of Metasequoia glyptostroboides Hu et Cheng . Their structures were elucidated by physical, chemical, and spectroscopic methods, including 1D‐ and 2D‐NMR and HR‐ESI‐MS. The cytotoxicites of the five compounds were tested against A549 and Colo 205 cell lines by the MTT method. |
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| Keywords: | Metasequoia glyptostroboides Norlignans Metasequirins G – I Phenylpropanoids |
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