Identification of Three New Flavonoids from the Peels of Citrus unshiu |
| |
Authors: | Hyun Ji Shin Joo‐Won Nam Ui Joong Yoon Ah‐Reum Han Eun‐Kyoung Seo |
| |
Institution: | 1. The Center for Cell Signaling & Drug Discovery Research, College of Pharmacy, Ewha Womans University, Seoul 120?–?750, Korea (phone: +82‐2‐32773047 (E.‐K. S.), +82‐2‐32773060 (A.‐R. H.);2. fax: +82‐2‐3277‐3051) |
| |
Abstract: | Three new flavonoids, 5,6,7,8,3′,4′‐hexamethoxyhomoflavone ( 1 ), 5,6,7,8,4′‐pentamethoxyhomoflavone ( 2 ) and 3,6,7,8,2′,5′‐hexamethoxyflavone ( 3 ) were isolated from the peels of mature fruits of Citrus unshiu Marcow (Rutaceae), together with the three known compounds 6,7,8,4′‐tetramethoxyflavone (=6,7,8‐trimethoxy‐2‐(4‐methoxyphenyl)‐4H‐1‐benzopyran‐4‐one), 3,5,7,8,2′,5′‐hexamethoxyflavone (=2‐(2,5‐dimethoxyphenyl)‐3,5,7,8‐tetramethoxy‐4H‐1‐benzopyran‐4‐one), and scopoletin (=7‐hydroxy‐6‐methoxy‐2H‐1‐benzopyran‐2‐one) of which the former two have never been isolated from natural resources, although they have been reported as synthetic compounds. The structures of 1 – 3 were elucidated on the basis of spectroscopic evidence, including 1D‐ and 2D‐NMR analysis. |
| |
Keywords: | Citrus unshiu Flavonoids Homoflavones Flavone 3 6 7 8 2′ 5′ ‐hexamethoxy‐ |
|
|