Antifungal Ursene‐Type Triterpene from the Roots of Alhagi camelorum |
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| Authors: | Abdul Hafeez Laghari Shahabuddin Memon Aisha Nelofar Khalid Mohammed Khan |
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| Affiliation: | 1. National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan, (phone: +92‐22‐2772065;2. fax: +92‐22‐2771560);3. Pakistan Council of Scientific and Industrial Research, Karachi‐75280, Pakistan;4. H.?E.?J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi‐75270, Pakistan (phone: +92‐21‐34824910;5. fax: +92‐21‐34819018) |
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| Abstract: | A new ursene‐type triterpene, (3β)‐30‐norurs‐11‐en‐3‐ol ( 1 ), was isolated from the MeOH extract of the roots of Alhagi camelorum. Its structure was elucidated on the basis of extensive spectroscopic investigations by 1D‐ and 2D‐NMR studies. In addition, 1 was evaluated for antifungal activities. Its application on prepared cultures of two fungi, i.e., Aspergillus niger and Saccharomyces cerevisiae, showed noticeable antifungal activity, suggesting that 1 could be used as a new promising agent in antifungal drug formulations. |
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| Keywords: | Alhagi camelorum Triterpenes Antifungal activity Ursene |
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