X‐Ray Structure Study of an Unusual 13,14,15,16‐Tetranorlabdane Derivative Obtained in the Synthesis of (7α)‐7,8‐Dihydroxy‐14,15‐dinorlabdane‐11,13‐dione |
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| Authors: | Victor C. Kravtsov Elena C. Gorincioi Alic N. Barba Aculina N. Aricu Janusz Lipkowski Pavel F. Vlad |
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| Affiliation: | 1. Institute of Applied Physics, Academy of Sciences of Moldova, Academiei Str. 5, MD‐2028, Chi?in?u, Republic of Moldova;2. Institute of Chemistry, Academy of Sciences of Moldova, Academei Str. 3, MD‐2028, Chi?in?u, Republic of Moldova;3. Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 4452, PL‐01224, Warzawa |
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| Abstract: | The unconventional (5S,7R,8S,9R,10S)‐configurated (?)‐7‐(acetyloxy)‐12,12‐dichloro‐8‐hydroxy‐13,14,15,16‐tetranorlabdan‐11‐one ( 2 ) was synthesized via the HCl‐promoted hydrolysis of (7α)‐7,8‐(isopropylidenedioxy)‐14,15‐dinorlabdan‐11,13‐dione ( 5 ). Possible mechanistic pathways of the reaction are considered. Crystal and molecular structures of the isolated compound 2 were determined by single‐crystal X‐ray structure analysis. |
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| Keywords: | X‐Ray crystallography Norlabdanes, halogenated Acetyl migration |
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