A Novel One‐Pot Synthesis of Fully Substituted Thiophen‐2(3H)‐ones Using N,N‐Disubstituted Thioamides |
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| Authors: | Hassan Zali‐Boeini Fatemeh Pourjafarian |
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| Institution: | 1. Department of Chemistry, University of Isfahan, 81746‐73441, Isfahan, Iran, (phone: +98‐311‐7932715;2. fax: +98‐311‐6689732) |
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| Abstract: | A new one‐step synthesis of highly substituted thiophen‐2(3H)‐one derivatives was developed. 2‐Aryl‐1‐(morpholin‐4‐yl)ethanethiones were reacted with 2‐chloro‐2‐phenylacetyl chloride in DMF in the presence of a base to give the title compounds in moderate‐to‐good yields. |
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| Keywords: | Thiophen‐2(3H)‐ones Thioamides |
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