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视觉非随意注意的近红外脑功能成像技术与事件相关脑电位检测技术研究
引用本文:李婷,李黎,杜鹏,骆清铭,龚辉.视觉非随意注意的近红外脑功能成像技术与事件相关脑电位检测技术研究[J].光学学报,2007,27(3):531-535.
作者姓名:李婷  李黎  杜鹏  骆清铭  龚辉
作者单位:华中科技大学生物医学光子学教育部重点实验室,武汉光电国家实验室(筹),武汉,430074
摘    要:近红外脑功能成像技术(fNIRI)是近年来发展起来的新技术,与心理学研究常用的事件相关脑电位检测技术(ERP)相比,能提供电生理信号之外的与脑功能活动相关的血液动力学信息。设计了非随意注意的经典范式,对同一组被试者分别使用近红外脑功能成像技术和事件相关脑电位检测技术检测其在实验过程中脑活动变化,然后对两种技术检测的结果进行处理和比较分析。结果发现近红外脑功能成像技术测出的非随意注意源定位在前额叶,与其相关P3a脑电皮层分布一致,甚至近红外脑功能成像技术测出的源定位范围可以缩小到Brodmann46区;血液激活先于P3a并在P3a完成后显著增强的现象支持深入研究脑机理的可能性。因此,近红外脑功能成像技术可有效地应用于脑的高级功能研究。

关 键 词:医用光学  血液动力学  非随意注意  近红外脑功能成像  事件相关脑电位检测技术
文章编号:0253-2239(2007)03-0531-5
收稿时间:2006/9/18
修稿时间:2006-09-18

Study of Ocular Nonselective Attention with fNIRI and ERP
Li Ting,Li Li,Du Peng,Luo Qingming,Gong Hui.Study of Ocular Nonselective Attention with fNIRI and ERP[J].Acta Optica Sinica,2007,27(3):531-535.
Authors:Li Ting  Li Li  Du Peng  Luo Qingming  Gong Hui
Institution:Key Laboratory of Biomedical Photonics of Ministry of Education, National Laboratory for Optoelectronics (Proposed
Abstract:Compared with event-related potential (ERP),which is widely used in psychological research,functional near-infrared imaging (fNIRI) is a new technique,and can supply hemodynamic information related with brain activity,excepting for electrophysiological signals.We conducted a series of experiments with the classic paradigm of ocular nonselective attention,monitored responses if brain with fNIRI and ERP respectively,and then analyzed the data.The results showed us that ocular nonselective attention companied activation was on the prefrontal lobe,which had the same results as its related P3a in ERP.In fact,the fNIRI results demonstrated a smaller area of the source than ERP,which was at the middle part of Brodmann 46,and the phenomenon that the hemodynamic activation occurred before P3a and strengthened just after P3a,supported the possibility of further study in brain mechanism. Therefore,fNIRI is a potential technique in advanced function research of brain.
Keywords:medical optics and biotechnology  hemodynamics  nonselective attention  functional near-infrared imaging  event-related potential
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