| AFacile and Highly Stereoselective Reductive Debromination of Anhydro-6- (R)-Hydroxyethyl- 6-Bromopenicillin |
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| 作者单位： | Bing ZHENG,Jin Long WU,Shao Jun XU,Jian Feng SHI(Department of Chemistry, Zhejiang University, Hangzhou 310027);Yao Zu CHEN(Department of Chemistry, Zhejiang University, Hangzhou 310027;National Laboratory of Applied Organic Chemistry,Lanzhou 730000) |
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| 摘 要： |
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A Facile and Highly Stereoselective Reductive Debromination of Anhydro-6- (R)-Hydroxyethyl- 6-Bromopenicillin |
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| Bing ZHENG,Jin Long WU,Shao Jun XU,Jian Feng SHI,Yao Zu CHEN. A Facile and Highly Stereoselective Reductive Debromination of Anhydro-6- (R)-Hydroxyethyl- 6-Bromopenicillin[J]. Chinese Chemical Letters, 2000, 41(5): 385-386 |
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| Authors: | Bing ZHENG Jin Long WU Shao Jun XU Jian Feng SHI Yao Zu CHEN |
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| Abstract: | Reductive debromination of anhydro-6-(R)-hydroxyethyl-6-bromopenicillin 7 by zinc in ammonium acetate gave 9 in 81% yield with high stereoselectivity of 6-(α):6-(β)=13:1. |
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| Keywords: | Reductive debromination stereoselectivity anhydro-6-(R)-hydroxyethyl-6-bromo-penicillin |
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