A novel one-pot pseudo-four-component isocyanide-based reaction: an unexpected approach for the synthesis of tetrahydrodiisoindoloquinoxalines and tetrahydrobenzodiisoindoloquinoxalines |
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| Authors: | Ahmad Shaabani Fatemeh HajishaabanhaMojtaba Mahyari Hamid MofakhamSeik Weng Ng |
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| Institution: | a Department of Chemistry, Shahid Beheshti University, G.C., PO Box 19396-4716, Tehran, Iran
b Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia |
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| Abstract: | A novel isocyanide based one-pot pseudo-four-component strategy for the synthesis of tetrahydrodiisoindoloquinoxaline and tetrahydrobenzodiisoindoloquinoxaline derivatives via the reaction of 1,2-diamines, 2-formylbenzoic acid, and an isocyanide at room temperature in good yields without using any catalyst and activation, is described. |
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| Keywords: | Quinoxaline Tetrahydroquinoxaline Indoloquinoxaline Multicomponent reaction Isocyanide |
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