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Stereoselective synthesis of macrolide-type antibiotics from epoxy amides. Synthesis of the polypropionate chain of streptovaricin u |
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| Authors: | Sarabia Francisco Sánchez-Ruiz Antonio Martín-Ortiz Laura García-Castro Miguel Chammaa Samy |
| Affiliation: | Department of Biochemistry, Molecular Biology and Organic Chemistry, Faculty of Sciences, University of Malaga, Campus de Teatinos s/n, 29071 Malaga, Spain. frsarabia@uma.es |
| Abstract: | The synthesis of the polypropionate chain of Streptovaricin U (1) is described utilizing a new approach for the stereoselective synthesis of the macrolide-type antibiotics via sulfur ylides. |
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