A new tigliane-type diterpene from Euphorbia dracunculoides Lam |
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| Authors: | Lin-Feng Dai Qian Liang Tie Liu Ming-Yu He Ping Zhao |
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| Affiliation: | 1. Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming, P.R. China;2. Department of Medicinal Plant, School of Forestry, Southwest Forestry University, Kunming, P.R. China |
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| Abstract: | One new tigliane-type diterpene, 4-deoxy-4(β)H-8-hydroperoxyphorbol-12-benzoate-13-isobutyrate (1), together with two known diterpenoids, 3-acetyl-5,8-dibenzoyl-14α-propanoyl-13,17-epoxy-7-myrsinaone diterpene with C9–C10 cyclised to form an additional lactone ring (2), Euphodendriane A (3) have been isolated from the whole plants of Euphorbia dracunculoides Lam. Their structures were elucidated by means of extensive spectroscopic analysis (NMR and HR-ESI-MS) and comparison with data reported in the literature. This is the first isolation of 8-hydroperoxy tigliane diterpene (1) from the genus of Euphorbia. All compounds were evaluated for their antifungal activities. |
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| Keywords: | Euphorbia dracunculoides diterpenoids hydroperoxy tigliane |
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