New flavonoid and pentacyclic triterpene from Sesamum indicum leaves |
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| Authors: | Nguyen Tien Dat Nguyen Hai Dang Le Nguyen Thanh |
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| Institution: | 1. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Cau Giay, Hanoi, Vietnamngtiend@imbc.vast.vn;3. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam |
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| Abstract: | Two new and one known compounds were isolated from the methanol extract of Sesamum indicum leaves. By means of spectroscopic methods, their structures were elucidated and identified to be 3-epibartogenic acid (1), kaempferol 3-O-2-O-(trans-p-coumaroyl)-3-O-α-L-rhamnopyranosyl]-β-d-glucopyranoside (2) and epigallocatechin (3). Compound 1 and 3 strongly inhibited α-amylase with the IC50 values of 146.7 and 303.9 μM, respectively, in comparison with acarbose (IC50 124.0 μM). |
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| Keywords: | Sesamum indicum Pedaliaceae 3-epibartogenic acid α-amylase |
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