Two new simple iridoids from the ant-plant Myrmecodia tuberosa and their antimicrobial effects |
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| Authors: | Nguyen Phuong Hanh Nguyen Huu Toan Phan Nguyen Thi Dieu Thuan Tran Thi Hong Hanh Le Thi Vien Nguyen Phuong Thao |
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| Institution: | 1. Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam;2. Tay Nguyen Institute for Scientific Research, VAST, Dalat, Vietnam;3. Institute of Marine Biochemistry, VAST, Hanoi, Vietnam |
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| Abstract: | Six iridoid derivatives (1–6), including two new compounds myrmecodoides A and B (1 and 2), were isolated from the ant-plant Myrmecodia tuberosa. Their structures were determined on the basis of spectroscopic data (1H and 13C NMR, HSQC, HMBC, 1H-1H COSY, NOESY and HR-ESI-MS) and by comparison with the literature values. Among isolates, 3 and 4 exhibit weak antibacterial effect against Staphylococcus aureus subsp. aureus with MIC value of 100.0 μg/mL. |
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| Keywords: | Myrmecodia tuberosa Rubiaceae ant-plant iridoid antimicrobial activity |
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