A new helvolic acid derivative from an endophytic Fusarium sp. of Ficus carica |
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| Authors: | Xi-Ai Liang Hong-Chi Zhang Rui Liu |
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| Institution: | 1. Key Laboratory of Auxiliary Chemistry &2. Technology for Chemical Industry Ministry of Education, Shaanxi University of Science &3. Technology, Xi’an, China;4. College of Agronomy and Life Science, Shanxi Datong University, Datong, China;5. College of Agronomy and Life Science, Shanxi Datong University, Datong, China |
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| Abstract: | A new helvolic acid derivative named helvolic acid methyl ester (1), together with two known helvolic acid compounds, helvolic acid (2) and hydrohelvolic acid (3), were isolated from the fermentation of endophytic fungus Fusarium sp. in Ficus carica leaves. Their structures were elucidated and identified by spectroscopic methods. Compounds 1–3 showed potent antifungal and antibacterial activities. |
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| Keywords: | Helvolic acid methyl ester endophytic fungus Fusarium sp Ficus carica antifungal activity |
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