Covalently assembled resorcin[4]arenes and molecular tweezers: a chiral recognition rationale by NMR |
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| Authors: | Gloria Uccello Barretta Federica Balzano Federica Aiello Francesca Nardelli Alessia Ciogli Andrea Calcaterra |
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| Affiliation: | 1. Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italygloria.uccello.barretta@unipi.it;3. Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy;4. Dipartimento di Chimica e Tecnologie del Farmaco, Università di Roma “La Sapienza”, Roma, Italy |
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| Abstract: | Chiral diamides and tetramidic resorcin[4]arenes deriving from (R,R)-1,2-diaminocyclohexane and (S,S)-1,2-diphenylethylendiamine, and a valine containing resorcin[4]arene have been compared by NMR in the enantiodiscrimination of mandelic acid. The relevance of cooperation between side arms and external surface of resorcin[4]arene core has been ascertained. |
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| Keywords: | NMR spectroscopy resorcin[4]arenes chiral auxiliaries stereochemistry host–guest systems |
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