A new Secondary metabolites of the crinoid (Comanthina schlegeli) associated fungus Alternaria brassicae 93 |
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| Authors: | Liu-Hong Zhang Hong-Wei Wang Jia-Yi Xu |
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| Institution: | 1. Schoolof Marine Sciences, SunYat-Sen University, Guangzhou, P.R. China;2. School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, P.R. China |
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| Abstract: | Fungus Alternaria brassicae 93 isolated from crinoid (Comanthina schlegeli), which was collected from the South China Sea. Six compounds were isolated from A. brassicae 93, including one new compound (1), along with five known compounds, ochratoxin A methyl ester (2), cis-4-hydroxym-ellein (3), (R)-7-hydroxymellein (4), trans-2-anhydromevalonic (5) and protocatechuic acid (6). Their structures were determined by spectroscopic methods and comparison with reported data. Cytotoxicity against two human cancer cell lines and antibacterial activity against twelve aquatic bacteria of compound 1 were also tested. |
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| Keywords: | Crinoid Alternaria brassicae associated fungus secondary metabolites |
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