A new phenolic compound with antioxidant activity from the branches and leaves of Pyrus pashia |
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| Authors: | Zhen-Jie Li Xi Zheng Chun-Ping Wan Le Cai Ying Li Lin Huang |
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| Institution: | 1. Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan 650091, China;2. Central Laboratory, No 1 Hospital Affiliated Yunnan University of Traditional Chinese Medicine, Kunming 650021, China |
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| Abstract: | The branches and leaves of Pyrus pashia are used to cure abdominal pain and diarrhoea in Chinese folk medicine. A new phenilic compound, 4-O-β-d-glucopyranosylbenzyl-benzoate ester (1), along with 21 known ones (2–22) were isolated from the branches and leaves of this plant. Compounds 2 and 3 displayed remarkable antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl radical (IC50 = 13.26 ± 0.04 μM, 13.28 ± 0.11 μM, respectively), which were at the same grade as positive control rutin. The caffeoyl group in compounds 2 and 3 was supposed to play an important role in the antioxidant activities. |
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| Keywords: | Pyrus pashia phenolic constituents antioxidant activity |
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