Three new acyltyramines from Anisodus luridus Link et Otto (Solanaceae) |
| |
Authors: | Lalit Kumar Lal Das Mradul Verma |
| |
Institution: | Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India |
| |
Abstract: | Three new acyltyramines, N-2-(4-hydroxyphenyl)ethyl]hentriacontanamide (1), N-2-(4-hydroxyphenyl)ethyl]nonacosanamide (2) and N-2-(4-hydroxyphenyl)ethyl]heneicosanamide (3) have been isolated from n-hexane extract of leaves of Anisodus luridus (Solanaceae). Successive extraction of defatted leaves of A. luridus with methanol afforded a residue on removal of solvent under reduced pressure. Residue was partitioned by means of chloroform and n-butanol. Chromatographic resolution of n-BuOH extract afforded six known compounds, apigenin (4), luteolin (5), quercetin (6), quercetin 3-O-α-l-rhamnoside (7), kaempferol 3-O-α-rhamnoside (8) and quercetin 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (9). The structures of the isolated compounds were assigned with the help of spectroscopic techniques. This is the first report of isolation of these compounds from this plant. |
| |
Keywords: | Anisodus luridus acyltyramines leaves Solanaceae |
|
|