Ugi reaction of thiouridocarboxylic acids: A synthesis of thiourea-peptoids |
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Authors: | Elnaz Ghasemi Ashraf S Shahvelayati |
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Institution: | 1. Department of Chemistry, Islamic Azad University, Science and Research Branch, Ponak, Tehran, Iran;2. Department of Chemistry, Islamic Azad University, Shahr-e Ray Branch, Tehran, Iran |
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Abstract: | Benzoylthioureidocarboxylic acids, prepared from benzoyl chlorides, potassium thiocyanate, and α-aminoacids, are used as acid components in the Ugi reaction to produce thiourea-peptoids in moderate to good yields. |
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Keywords: | Ugi reaction peptoid peptide mimics thioureidocarboxylic acid isocyanide α-amino acid |
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