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Chemical composition of the essential oil from Thapsia garganica L. (Apiaceae) grown wild in Sicily and its antimicrobial activity
Authors:Simona Casiglia  Luana Riccobono  Sergio Rosselli  Federica Senatore  Felice Senatore
Institution:1. Department STEBICEF, University of Palermo, Palermo, Italy;2. Department of Pharmacy, University of Salerno, Fisciano, Italy;3. Department of Pharmacy, University of Naples “Federico II”, Naples, Italy
Abstract:In this study, the chemical composition of the essential oil from flowers and leaves of Thapsia garganica L. collected in Sicily was evaluated by GC and GC–MS. The main components of T. garganica flower oil (T.f.) were chamazulene (58.3%), humulene oxide II (9.0%), tricosane (8.2%) and pentacosane (8.2%). Also the oil from leaves (T.l.) was characterised by high content of chamazulene (49.2%). Other abundant metabolites were 1,4-dimethylazulene (18.5%), (E)-phytol (6.3%) and neophytadiene (5.1%). The comparison with other studied oils of genus Thapsia is discussed. Antimicrobial activity against several micro-organisms, including some ones infesting historical art craft, was also determined.
Keywords:Thapsia garganica  Apiaceae  volatile components  chamazulene  1  4-dimethylazulene  humulene oxide II  antimicrobial activity
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