A new polyketide,penicillolide from the marine-derived fungus Penicillium sacculum |
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Authors: | Tao Liu Songya Zhang Zhanlin Li Yu Wang Zaixing Chen Jiao Bai |
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Affiliation: | 1. Department of Natural Products Chemistry, School of Pharmacy, China Medical University, Shenyang, Chinataoliu0307@163.com;3. Key Laboratory of Structure-Based Drug Design &4. Discovery, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China;5. Department of Natural Products Chemistry, School of Pharmacy, China Medical University, Shenyang, China;6. Department of the Central Laboratory, School of Pharmacy, China Medical University, Shenyang, China |
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Abstract: | A new polyketide, penicillolide (1) was isolated from the fermentation broth of the marine-derived fungus Penicillium sacculum GT-308. Compound 1 is a polyketide with a unique carbon skeleton. The structure of this compound was established via extensive spectroscopic analyses including 1D-, 2D-NMR, and HRESI-MS. |
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Keywords: | Marine-derived fungus Penicillium sacculum polyketide penicillolide |
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