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A new megastigmane sulphoglycoside and polyphenolic constituents from pericarps of Garcinia mangostana
Authors:Thu Huong Tran  Tram Le Huyen  Thi Minh Tran  Tuan Anh Nguyen  Thanh Binh Pham
Institution:1. School of Chemical Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam;2. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
Abstract:A megastigmane sulphoglycoside together with three phenolic compounds were isolated from the water-soluble fraction of the pericarps of Garcinia mangostana. The structure of the new compound was determined as 4-O-sulpho-β-d-glucopyranosyl abscisate (1) by spectroscopic data. Proanthocyanidin A2 (2) showed potent α-glucosidase inhibitory and DPPH scavenging activities with IC50 values of 3.46 and 11.6 μM, respectively.
Keywords:Garcinia mangostana  megastigmane sulphoglycoside  proanthocyanidin A2  α-glucosidase  DPPH
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