A new lupane-type triterpenoid fatty acid ester and other isolates from Ophiorrhiza shendurunii |
| |
| Authors: | Renjith Rajan Ramaswamy Venkataraman |
| |
| Affiliation: | 1. Phytochemistry and Phytopharmacology Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Thiruvananthapuram, India;2. Department of Chemistry, Sri Paramakalyani College, Manonmaniom Sundaranar University, Tirunelveli, India |
| |
| Abstract: | A new pentacyclic triterpenoid fatty acid ester, lupan-20-ol-3(β)-yl hexadecanoate (1), together with lupan-20-ol-3(β)-yl acetate (2), olean-18-en-3(β)-yl hexadecanoate (3), dotriacontanoic acid (4), stigmasterol (5), rubiadin (6), nonadecanoic acid (7), palmitic acid (8) and camptothecin (9) were isolated from the hexane and chloroform extracts of Ophiorrhiza shendurunii from South India. Structures of the isolates were determined by 1H, 13C, 13C DEPT, 1H–1H COSY, HMBC, HSQC, NOESY NMR, FT-IR, DART-MS, ESI-MS, alkaline hydrolysis, derivatisation, GC–MS and HPTLC analyses. O. shendurunii hexane and chloroform extracts showed significant activities against Candida albicans and Fusarium oxysporum. Compounds 1 to 3 showed only moderate antiyeast/antifungal activities. |
| |
| Keywords: | Ophiorrhiza shendurunii pentacyclic triterpenoid fatty acid ester lupan-20-ol-3(β)-yl hexadecanoate antifungal activity |
|
|
