New alkaloids from the leaves of Evodia rutaecarpa |
| |
| Authors: | Xiao Xia Jian-Guang Luo Rui-Huan Liu Ming-Hua Yang |
| |
| Institution: | State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, People’s Republic of China |
| |
| Abstract: | One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known alkaloids (3–11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginosa with an MIC value of 7.13 μg/ml. |
| |
| Keywords: | Rutaceae Evodia rutaecarpa quinolone alkaloids indole alkaloids antibacterial activity |
|
