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Two new compounds from Melodinus suaveolens
Authors:Tian Dong Zhang  Bao Kun Zhu  Jun Ling  Qian Xu Yang
Affiliation:1. R&2. D, China Tobacco Yunnan Industrial Co. Ltd, Kunming, China
Abstract:Two new compounds, 19-hydroxy-melodinine K (1) and melodiside (2), and 25 known compounds were isolated from leaves and twigs of Melodinus suaveolens. Their structures were elucidated based on 1- and 2-D NMR, FTIR, UV and MS spectroscopic data. 19-hydroxy-melodinine K showed cytotoxic activity against MDA-MB-231 breast, BCG-823 gastric, SW480 colon and Hela cancer cells.
Keywords:Melodinus suaveolens  19-hydroxy-melodinine K  melodiside  cytotoxicity
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