A new dimeric anthraquinone from endophytic Talaromyces sp. YE3016 |
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| Authors: | Xiao-Song Xie Xiao-Wei Fang Rong Huang Shou-Peng Zhang Hong-Xia Wei |
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| Institution: | 1. Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan Institute of Microbiology, Yunnan University, Kunming, P.R. China;2. School of Chemical Science and Technology, Yunnan University, Kunming, P.R. China |
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| Abstract: | A new unsymmetrical dimeric anthraquinone, 3-demethyl-3-(2-hydroxypropyl)-skyrin (1) was isolated from the solid-state fermentation extract of an endophytic fungal strain Talaromyces sp. YE 3016, together with five known compounds, skyrin (2), oxyskyrin (3), emodin (4), 1,3,6-trihydroxy-8-methyl-anthraquinone (5) and ergosterol (6). The structure of the new compound was elucidated on the basis of spectroscopic analysis. Compounds 1–3 exhibited moderate cytotoxic activities against MCF-7 cell line. |
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| Keywords: | Talaromyces sp endophytic fungi dimeric anthraquinone skyrin |
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