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Synthesis of 5,6‐Diarylpyridin‐2(1H)‐ones from Isoflavones
Authors:Mulin Zhu  Zunting Zhang  Dong Xue  Jinfeng Qiao  Yong Liang  Stanislaw F. Wnuk
Affiliation:1. Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, Shannxi 710062, China;2. Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States
Abstract:A simple method for the cyclocondensation of substituted isoflavones with cyanoacetamide in the presence of sodium hydroxide to give an array of 3‐cyano‐5,6‐diarylpyridin‐2(1H)‐ones in good yields is reported.
Keywords:isoflavones  cyclocondensation  3‐cyano‐5,6‐diarylpyridin‐2(1H)‐ones
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