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Enantiospecific Photochemical Transformations under Elevated Pressure |
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| Authors: | Anoklase J‐L Ayitou Dr Gaku Fukuhara Elango Kumarasamy Prof Dr Yoshihisa Inoue Prof Dr J Sivaguru |
| Institution: | 1. Department of Chemistry and Biochemistry, North Dakota State University, 1231 Albrecht Blvd., Fargo, ND 58103 (USA), Fax: (+1)?701‐231‐8831;2. Department of Applied Chemistry, Osaka University, 2‐1 Yamada‐oka, Suita, Osaka 565‐0871 (Japan), Fax: (+81)?6‐6879‐7923 |
| Abstract: | Enantiospecific axial‐to‐point chiral transfer in light‐induced transformations was efficient under elevated pressure at high temperatures. Model photoreactions with atropisomeric compounds showed higher enantioselectivity in the photoproducts under elevated pressure. The ee values in the photoproducts were rationalized based on the increased stability of optically pure atropisomeric compounds at elevated pressure, even at high temperatures. |
| Keywords: | asymmetric synthesis atropisomerism enantioselectivity photochemistry pressure effects Non‐biaryl atropisomers |