The “Click” Reaction Involving Metal Azides,Metal Alkynes,or Both: An Exploration into Multimetal Structures

Cu^I‐catalyzed 1,3‐cycloaddition of azides and alkynes (CuAAC) is one of the most powerful synthetic methodologies known. However, its use to prepare well‐defined multimetallic structures is underdeveloped. Apart from the applications of this reaction to anchor different organometallic reagents to surfaces, polymers, and dendrimers, only isolated examples of CuAAC with metal–η¹‐alkyne and metal–azide complexes to prepare multimetal entities have been reported. This concept sketches the potential of these reactions not only to prepare “a la carte” multimetal 1,2,3‐triazole derivatives, but also to discover new and unprecedented reactions.