Enantioselective Synthesis of Alcohols and Amines by Iridium‐Catalyzed Hydrogenation,Transfer Hydrogenation,and Related Processes |
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| Authors: | Dr Agnieszka Bartoszewicz Dr Nanna Ahlsten Prof Dr Belén Martín‐Matute |
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| Institution: | 1. Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, 106 91 Stockholm (Sweden), Fax: (+46)?8‐15‐49‐08;2. A. Bartoszewicz, N. Ahlsten, B. Martín‐Matute, Berzelii Centre EXSELENT on Porous Materials, Stockholm University, 106 91 Stockholm (Sweden) |
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| Abstract: | The preparation of chiral alcohols and amines by using iridium catalysis is reviewed. The methods presented include the reduction of ketones or imines by using hydrogen (hydrogenations), isopropanol, formic acid, or formate (transfer hydrogenations). Also dynamic and oxidative kinetic resolutions leading to chiral alcohols and amines are included. Selected literature reports from early contributions to December 2012 are discussed. |
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| Keywords: | asymmetric catalysis hydrogenation iridium oxidation transfer hydrogenation |
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