Bis(phosphite) Ligands with Distal Regulation: Application in Rhodium‐mediated Asymmetric Hydroformylations |
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| Authors: | Ignasi Mon Dr. D. Amilan Jose Prof. Anton Vidal‐Ferran |
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| Affiliation: | 1. Institute of Chemical Research of Catalonia (ICIQ), Avgda. Pa?sos Catalans 16, 43007 Tarragona (Spain), Fax: (+34)?977920228;2. Catalan Institution for Research and Advanced Studies (ICREA), Passeig Lluís Companys 23, 08010 Barcelona (Spain) |
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| Abstract: | Small amounts of achiral polyether binders are employed to enhance the enantioselectivity of the hydroformylation of an array of diversely substituted substrates (increase of up to 62 % ee for vinyl acetate) mediated by chiral rhodium complexes derived from the α,ω‐bis(phosphite)–polyether ligands 1 . To the best of our knowledge, this study represents an unprecedented successful example of the positive regulation of enantioselectivity in hydroformylations. |
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| Keywords: | alkenes asymmetric catalysis enantioselectivity hydroformylation rhodium |
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